Semaglutide Tablets

Mimics GLP-1, a naturally occurring hormone produced in your gut that helps regulate blood sugar and your digestive system.

Semaglutide Tablets

Mimics GLP-1, a naturally occurring hormone produced in your gut that helps regulate blood sugar and your digestive system.
$299/mo
HSA / FSA Eligible

Same-day assessment and free 2-day shipping

Each batch of medication undergoes quality testing

Doctor-prescribed medication, made for you

100% online care
Doctor-prescribed
Pharmacy-prepared
Same-day assessment
Free shipping
24/7 support
100% online care
Doctor-prescribed
Pharmacy-prepared
Same-day assessment
Free shipping
24/7 support
What are Compound Semaglutide Tablets?

Semaglutide tablets are a daily, needle-free GLP-1 treatment that works with your body’s natural appetite hormones to help you feel full sooner and support weight loss. Willow’s compounded formulation is designed with your doctor and personalized to your health profile and goals.

A personalized plan can help you stay on track. Your doctor can adjust your treatment as your needs change, and your Care Team is available 24/7. It’s your treatment, made for you.

Compounded semaglutide tablets are not approved by the FDA, and the FDA does not review compounded medications for safety, effectiveness, or quality. These medications are prepared by state-licensed compounding pharmacies that operate under state board of pharmacy oversight and are required to meet USP compounding standards.

How do I take Semaglutide tablets?

Compound Semaglutide tablets are administered via daily doses under the tongue. They are a popular alternative for patients that are uncomfortable with self-injections. Sublingual medication works by placing the drug under the tongue, where it dissolves and is absorbed directly into the bloodstream through the tissues. The area under the tongue has a rich supply of blood vessels, which allows the medication to bypass the digestive system and liver.

The Willow difference

US-licensed doctors
Transparent pricing, no hidden fees
Needle-free options
24/7 human support
Zero judgment
Others
Nurse practitioners or physician assistants
Add-on fees for visits or follow-ups
Injectable only
AI-powered support
Comes with a lecture

Tablet and injectable treatment options

Personalized tablets and injectable plans guided by licensed doctors, designed to put choice and confidence back in your hands.

The science behind Semaglutide Tablets

When you eat, the food stimulates your gut to release the GLP-1 hormone. GLP-1 helps lower blood glucose (blood sugar) by triggering insulin release. Insulin helps blood glucose enter your body’s cells for later energy use.
‍
In some people, the gut doesn't make enough natural GLP-1, or the brain isn't sensitive to it.
‍
Semaglutide is a synthetic GLP-1 RA (receptor agonist). A drug that works as an agonist activates the same cell receptors as the body’s natural hormones. Semaglutide works in the gut like the body’s natural GLP-1, slowing digestion, curbing hunger, and signaling fullness to the brain.

How does it feel to take Semaglutide Tablets?

Willow patients report:

No more random snack cravings throughout the day

Smaller portions feel just as satisfying as large ones used to

The feeling of being full lasts longer after meals

Getting started with Willow

Three simple steps to weight loss care

1
Assessment
and review
FSA & HSA eligible
Answer a few questions about your health and goals. A US-licensed physician reviews your assessment, usually within 24 hours. If treatment is right for you, they'll confirm your prescription.
FSA & HSA eligible
2
Preparation
and shipping
Your prescription is prepared by trusted US pharmacy partners. It ships with tracking, so you always know where it is.
FSA & HSA eligible
3
Delivery
and support
Your treatment arrives in discreet packaging. From there, you'll have unlimited doctor messaging and 24/7 Care Team support.
FSA & HSA eligible

Getting started with Willow

Three simple steps to weight loss care
1
Assessment and review
Answer a few questions about your health and goals. A US-licensed physician reviews your assessment, usually within 24 hours. If treatment is right for you, they'll confirm your prescription.
FSA & HSA eligible
2
Preparation and shipping
Your prescription is prepared by trusted US pharmacy partners. It ships with tracking, so you always know where it is.
FSA & HSA eligible
3
Delivery and support
Your treatment arrives in discreet packaging. From there, you'll have unlimited doctor messaging and 24/7 Care Team support.
FSA & HSA eligible

Prescribed by U.S. licensed doctors

Willow care is led by experienced, U.S. licensed doctors who guide treatments with intention, expertise, and ongoing support.

Personalized care on your time

No office visits. 100% online. Free, regular follow-ups from your Willow Care Team.

Clinically-informed GLP-1 careGLP-1 care

GLP-1 medications backed by clinical research, prepared by licensed pharmacies, and tailored for your treatment plan.

Questions we hear everyday

Do I need to make changes to my diet with Compound Semaglutide?

We believe in a sustainable and flexible approach to nutrition, without imposing limitations on your diet. Our goal is to guide you in establishing healthy eating habits, complemented by the medication's ability to decrease appetite and 'food noise.' We encourage maintaining a nourishing, high-protein diet, and many patients report losing weight without needing uncomfortably restrictive dieting or calorie counting.

What are the side effects for Semaglutide?

Common side effects of semaglutide are usually mild and may include:

• Nausea

• Vomiting

• Diarrhea

• Constipation

• Abdominal pain

• Decreased appetite

• Indigestion


The majority of side effects are transient and typically resolve spontaneously. Nevertheless, if side effects persist or deteriorate, seek guidance from a healthcare professional.

Willow also offers Odansetron to manage side effects if they occur. This medication is commonly used to prevent nausea and vomiting.

‍

Semaglutide Patient Safety Information

What happens if I stop the medication?

When stopping Semaglutide abruptly, some patients may experience mild to moderate weight gain. Others may maintain the weight loss they achieved while on the medication. We recommend patients work with their Willow physician to slowly decrease their dose in order to maintain their weight loss achievements.

You may notice an increase in appetite and a return of food cravings, allowing you to eat more without feeling as full. By gradually tapering off the medication with your physician’s guidance, you can better manage these changes and maintain your health and wellness goals.

How do I take Semaglutide Tablets?

Semaglutide Tablets are taken once a day, ideally in the morning. Here’s how to do it:

  1. Rinse: If you’ve eaten or had anything to drink, rinse your mouth with water.
  2. Place: Put the tablet under your tongue and do not swallow.
  3. Dissolve: Let it fully dissolve under your tongue without swallowing the tablet.
  4. Wait: Once no taste remains, you can eat or drink again.

More from our members

4.9/5 (2200 + 5 star reviews)
"Highly recommend Willow! I've had a very positive experience with this company. My doctor is helpful and quick to respond. Shipping has been on time every month. I had one issue at the very beginning where I was missing one of the tablets prescribed, the client services team quickly responded and had the pharmacy send it to me within days."
Chelsea S.
"My experience with Willow has been excellent. Communication has been great with the doctors and staff. I've always received my medication in a timely matter. I would highly recommend this company to anyone who is interested in taking a GLP-1."
Laura O.
"I was 100% satisfied with the experience, then Willow managed to improve the experience even more when a non-weight loss related issue came up suddenly. I could not have asked for better response time & actions taken. I'm so happy I chose Willow given all of the providers out there."
Susan K.
"Nothing but a good experience with Willow. I'm almost to my goal weight. I've lost 25 lbs. From the doctors to the staff everyone is great and very responsive. I've referred a friend and she is having a great experience too. Highly recommended!"
Olga C.
"I've been using Willow for 4 months now and although they are a bit more expensive than other sites for GLP, I am sticking with them because I appreciate the fast response and personal physician care. Many other sites just dole out meds unsupervised and it's impossible to get a hold of a human. I also feel like their GLP combo with Vitamin B is really helpful."
Meg T.
"Really good experience with the Willow team. They understood my issues and helped me stay motivated. The options are easy and the meal suggestions are tasty which easily helps when trying new things. It has been more about learning way of life and habit building for me so this was all really helpful."
Rudi V.
"I've had such a great experience from start to finish. The customer service is outstanding (thanks Mallory) and every question I had for the doctor or the team was answered quickly and with real care. Thanks to their support, I've reached my goal and finally lost the weight I couldn't lose on my own. I highly recommend them to anyone on a similar journey!"
Romy H.
"This is the first time in YEARS that I've enjoyed looking in the mirror! I've lost 22 lbs, but more than that, my confidence has been restored. The support from their team is amazing (shoutout Jethel and Dr Green), and I love how easy it is to adjust shipments. Seriously, if you're on the fence, just go for it!"
Megan C.